And the nominees are:
Molly McGrue and the unicorn (The Last Unicorn)
Selina Kyle and Bruce Wayne (Batman Returns)
Rick Deckard and Rachael (Blade Runner)
Uh...everybody in this one, basically (but this is the pair that makes me cry the most--who knows why) (Crouching Tiger, Hidden Dragon)
I defy you not to sob during the last half hour of this film. (The Remains of the Day)
Holden and Amy, sure, but really...Holden and Banky are the sadder loss. And there's no cute youtube clip of their break-up, it being a bromance, but here's the former. (Chasing Amy)
Ivy Walker and Lucius Hunt (The Village)
Pocahontas and Captain Smith, or Old World and New (The New World)
Charlotte and Bob Harris, (Lost in Translation)
For so many reasons, Kim and Edward (Edward Scissorhands)
These I disqualified because one or both parties were a) dead--which really needs its own contest--b) just too creepy to count or c) Ralph Fiennes, and that's kinda like cheating:
Claire Dolan, The Constant Gardener, The English Patient, Romeo is Bleeding, Rushmore, Talk To Her, Y Tu Mama Tambien, Waterland, Closer, The Dangerous Lives of Altar Boys, Nowhere, Ghost, Truly Madly Deeply, High Art, May, XXY, The Crying Game, and possibly Heaven. I could go on...and I'm sure I will in another blogpost some time. But for this moment, here are the Nopes.
And also also, honorable mention has to go to the Taraji Henson and Alicia Keyes assassin duo in Smokin' Aces; it can't count fully since it's better placed in the subcat of Tragically Unrequited Super Hot Love Bombs.